ACTH Testing for Cushing's Disease
What is ACTH?
ACTH (Adrenocorticotropic Hormone) is a hormone produced by the pituitary gland. It stimulates the adrenal glands to produce cortisol, which is important for stress response, metabolism, and overall health.
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Why Does My Pet Need This Test?
An ACTH Stimulation Test may be recommended to help diagnose or monitor certain hormonal conditions, including:
Cushing’s disease (hyperadrenocorticism): when the body produces too much cortisol.
Addison’s disease (hypoadrenocorticism): when the body does not produce enough cortisol.
Monitoring treatment: to ensure medications (such as trilostane) are working effectively and safely.
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How to Prepare Your Pet
Fasting:
In most cases, your pet should be fasted for 8–12 hours prior to the test (water is fine unless advised otherwise).Medications:
If your dog is on trilostane, give the normal morning dose, and we will perform the test 4–6 hours later.
Please let us know about all medications your pet is receiving, especially steroids (e.g. prednisolone), as these can affect results.Routine:
Try to keep your pet’s morning routine as normal, offer a small walk toilet and keep as calm as possible to avoid unnecessary stress.
How it Works
An ACTH Stimulation Test is safe and minimally invasive:
A baseline blood sample is taken from your pet
A small injection of Synthetic ACTH is given to stimulate the adrenal glands.
A second blood sample is collected one hour later to measure how the adrenal glands respond.
The sample is then sent to our Laboratory for testing, with results returning within a few days.
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What Happens During Testing?
Your pet will need to remain calm and rested between samples.
You may choose to leave your pet in hospital with us, or take your pet home and return at the scheduled time for the second blood sample.
Most pets tolerate the procedure very well and can go home immediately after the second sample is taken.
After Your Test
Your pet can return to normal activity, feeding, and routine unless otherwise advised.
There are typically no side effects from the ACTH injection.
Results are sent to an external laboratory, and we usually receive them within a few days.
A veterinarian will contact you to discuss the results and any next steps or treatment adjustments.
FAQs
Here are some common questions about senior pet care and our recommendations.
Typically, pets are considered senior around 7 years old. However, this can vary based on breed and size. Larger breeds may age faster than smaller ones.
Yes, we recommend checkups every six months for senior pets. This allows us to monitor their health closely. Regular visits can help catch any issues early.
We may suggest blood and urine tests to assess overall health. Blood pressure checks and imaging can also be beneficial if concerns arise. These proactive measures help ensure your pet's well-being.
Absolutely, we provide various treatments for arthritis and stiffness. Options include medication, supplements, and movement support. Our goal is to enhance your pet's comfort and mobility.
Yes, senior pets often require different nutritional needs. We can guide you in selecting age-appropriate food. Proper nutrition is crucial for maintaining their health.
We can assess their cognitive function and recommend support.
Still have questions?
Contact us for more information.
Good care starts with Mosman Vet
Whether it’s a routine check-up, an unexpected issue or ongoing care, we’re here to help you make the best decisions for your pet’s health and wellbeing.